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When it comes to Repentance new items, there are still combos that fans are figuring out months after the DLC was released. Items like Quints, which create hordes of followers, can be easily broken in The Binding of Isaac's alternate Greed Mode while being not so useful in a normal run.
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Updated Augby Erik Petrovich: Part of what makes The Binding of Isaac: Repentance so replayable is the completely unique items that the new DLC gives players. Edmund McMillen, the creator of the game, even said that the new meta's difficulty is meant to force fans to try new methods of completing runs. While some fans claim the new expansion is much more difficult than Afterbirth or Afterbirth+, there are many new items that either flat out break the game or combine well with just about anything.
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It wraps up the story and adds hundreds of new items, trinkets, two new characters, and new paths for the player to take – and there are a lot of new Binding of Isaac Repentance items. The Binding Of Isaac: Repentance is the third and final expansion for the Binding of Isaac series.
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